A magnitude 7.5 (major) earthquake struck 39 km NW of Yurimaguas, Peru on 2005-09-26 01:55 UTC, at a depth of 115 km. See it live on Earth Live's real-time 3D globe.
Source: USGS event page. The TNT equivalent is computed from the magnitude with the standard Gutenberg–Richter energy relation; all other figures are USGS's own.
In the year before this quake, USGS recorded 18 earthquakes of magnitude 2.5 or more within 300 km.
Strongest recorded within 300 km since 1900:
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